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Lipid-mediated delivery of CD47 siRNA aids JQ1 in ensuring simultaneous downregulation of PD-L1 and CD47 and improves antitumor immunotherapy efficacy . Yong Li, Xianying Meng, Guang Chen, Yue Hou, Xuan Wu, Jialiang Wang, Xiuxiu Cong, Kuirong Mao, Chenxi Wu, Hongmei Chen, Xu Sun, Jingjing Zhou, Ye Wang, Yong-Guang Yang, Tianmeng Sun
, Biomater. Sci.
, 2022
, 10
, 6755
Tumor localization of oncolytic adenovirus assisted by pH-degradable microgels with JQ1-mediated boosting replication and PD-L1 suppression for enhanced cancer therapy . Haishi Qiao, Xingmei Chen, Qiming Wang, Junmei Zhang, Dechun Huang, Enping Chen, Hongliang Qian, Yinan Zhong, Qi Tang, Wei Chen
, Biomater. Sci.
, 2020
, 8
, 2472
Enzyme-responsive micellar JQ1 induces enhanced BET protein inhibition and immunotherapy of malignant tumors . Zhenqi Zhang, Qiang Zhang, Jiguo Xie, Zhiyuan Zhong, Chao Deng
, Biomater. Sci.
, 2021
, 9
, 6915
A polymeric IDO inhibitor based on poly(ethylene glycol)-b -poly(l -tyrosine-co -1-methyl-d -tryptophan) enables facile trident cancer immunotherapy . Yuanyuan Liu, Jiguo Xie, Xiaofei Zhao, Yueyue Zhang, Zhiyuan Zhong, Chao Deng
, Biomater. Sci.
, 2022
, 10
, 5731
Targeting Brd4 for cancer therapy: inhibitors and degraders . Yingchao Duan, Yuanyuan Guan, Wenping Qin, Xiaoyu Zhai, Bin Yu, Hongmin Liu
, Med. Chem. Commun.
, 2018
, 9
, 1779
Structure-based virtual screening of novel, high-affinity BRD4 inhibitors . Charuvaka Muvva, E. R. Azhagiya Singam, S. Sundar Raman, V. Subramanian
, Mol. BioSyst.
, 2014
, 10
, 2384
Photo-Brook rearrangement of acyl silanes as a strategy for photoaffinity probe design . Annika C. S. Page, Spencer O. Scholz, Katherine N. Keenan, Jessica N. Spradlin, Bridget P. Belcher, Scott M. Brittain, John A. Tallarico, Jeffrey M. McKenna, Markus Schirle, Daniel K. Nomura, F. Dean Toste
, Chem. Sci.
, 2022
, 13
, 3851
Stereoselective synthesis of allele-specific BET inhibitors . Adam G. Bond, Andrea Testa, Alessio Ciulli
, Org. Biomol. Chem.
, 2020
, 18
, 7533
Chirality: a key parameter in chemical probes . Andrew McGown, Jordan Nafie, Mohammed Otayfah, Storm Hassell-Hart, Graham J. Tizzard, Simon J. Coles, Rebecca Banks, Graham P. Marsh, Hannah J. Maple, George E. Kostakis, Ilaria Proietti Silvestri, Paul Colbon, John Spencer
, RSC Chem. Biol.
, 2023
, 4
, 716
Click chemistry in the development of PROTACs . Ce Yang, Ravi Tripathi, Binghe Wang
, RSC Chem. Biol.
, 2024
, 5
, 189